| June 1918 | Started medical products wholesale business |
| October 1947 | Registered Kosakai Chemical Industry Co., Ltd. |
| November 1960 | Relocated head office to Nihonbashimuromachi, dealt with food additives and food packing materials |
| April 1971 | Established Osaka office |
| October 1987 | Increased capital amount to 40million yen |
| April 1991 | Established Shizuoka office |
| September 2015 | Moved head office to Nihonbashitomizawacho |
| June 2018 | 100th anniversary |
| May 2023 | Established Fukuoka sub-office |
| March 2024 | Established Tokyo sales-office (TSO) |

